DPI-3290

DPI-3290, Burroughs Wellcome'daki bilim adamları tarafından keşfedilmiş ve Delta Pharmaceutical'a^[1] ruhsatlandırılmıştır ve bilimsel araştırmalarda kullanılan bir ilaçtır. Güçlü bir analjezik ilaçtır,^[2] çok az solunum depresyonu üretir.^[3]

Kaynakça

^ US Patent 5552404 - Opioid compounds and methods for using same
^ "DPI-3290 [(+)-3-((alpha-R)-alpha-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl)-N-(3-fluorophenyl)-N-methylbenzamide]. I. A mixed opioid agonist with potent antinociceptive activity". The Journal of Pharmacology and Experimental Therapeutics. 307 (3): 1221-6. December 2003. doi:10.1124/jpet.103.054361. PMID 14534368.
^ "DPI-3290 [(+)-3-((alpha-R)-alpha-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl)-N-(3-fluorophenyl)-N-methylbenzamide]. II. A mixed opioid agonist with potent antinociceptive activity and limited effects on respiratory function". The Journal of Pharmacology and Experimental Therapeutics. 307 (3): 1227-33. December 2003. doi:10.1124/jpet.103.054429. PMID 14534367.

[1] US Patent 5552404 - Opioid compounds and methods for using same

[2] "DPI-3290 [(+)-3-((alpha-R)-alpha-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl)-N-(3-fluorophenyl)-N-methylbenzamide]. I. A mixed opioid agonist with potent antinociceptive activity". The Journal of Pharmacology and Experimental Therapeutics. 307 (3): 1221-6. December 2003. doi:10.1124/jpet.103.054361. PMID 14534368.

[3] "DPI-3290 [(+)-3-((alpha-R)-alpha-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl)-N-(3-fluorophenyl)-N-methylbenzamide]. II. A mixed opioid agonist with potent antinociceptive activity and limited effects on respiratory function". The Journal of Pharmacology and Experimental Therapeutics. 307 (3): 1227-33. December 2003. doi:10.1124/jpet.103.054429. PMID 14534367.

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