Yarık damak-dil bağı sendromu

Yarık damak-dil bağı sendromu (cleft palate-ankyloglossia syndrome; CPX sendromu), X-kromozomu aracılığıyla aktarılan kalıtsal bir sendromdur.^[1]^[2]^[3]

3 bulgudan oluşur:^[1]^[2]^[3]

Yarık damak (tam olmayan bir yarık vardır)
Palatofaringeal yetersizlik (yumuşak damak ve farenks kasları güçsüzdür)
Ankyloglossia (dil ile ağız tabanı arasındaki bağ kalın ve kısadır)

Kaynakça

^ ^a ^b Rushton AR. Sex-linked inheritance of cleft palate. Human Genetics, 48: 179-181, 1979
^ ^a ^b Forbes SA, Richardson M, Brennan L, et al. Refinement of the X-linked cleft palate and ankyloglossia (CPX) localisation by genetic mapping in an Icelandic kindred. Human Genetics, 95: 342-346, 1995
^ ^a ^b Cohen MM Jr. Malformations of the Craniofacial Region: Evolutionary, Embryonic, Genetic, and Clinical Perspectives. American Journal of Medical Genetics (Seminars in Medical Genetics), 115:245-268, 2002

[:0-1] Rushton AR. Sex-linked inheritance of cleft palate. Human Genetics, 48: 179-181, 1979

[:1-2] Forbes SA, Richardson M, Brennan L, et al. Refinement of the X-linked cleft palate and ankyloglossia (CPX) localisation by genetic mapping in an Icelandic kindred. Human Genetics, 95: 342-346, 1995

[:2-3] Cohen MM Jr. Malformations of the Craniofacial Region: Evolutionary, Embryonic, Genetic, and Clinical Perspectives. American Journal of Medical Genetics (Seminars in Medical Genetics), 115:245-268, 2002

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